diff --git a/Jenkinsfile b/Jenkinsfile
new file mode 100644
index 0000000..ab01100
--- /dev/null
+++ b/Jenkinsfile
@@ -0,0 +1,36 @@
+pipeline {
+    agent any
+    stages {
+        stage("clean") {
+            steps {
+                sh 'rm -rf ./dist/*'
+            }
+        }
+        stage("install") {
+            steps {
+                sh 'mamba env update --file environment.yml'
+                sh 'echo "mamba activate filterfasta" >> ~/.bashrc'
+            }
+        }
+        stage("build") {
+            steps {
+                sh "python -m build"
+            }
+        }
+        stage("test") {
+            steps {
+                sh "pip install dist/*.whl"
+            }
+        }
+        stage("publish") {
+            when {
+                branch '**/master'
+            }
+            steps {
+                withCredentials([usernamePassword(credentialsId: 'rs-git-package-registry-ydeng', passwordVariable: 'PASS', usernameVariable: 'USER')]) {
+                    sh "python -m twine upload --repository-url https://git.reslate.systems/api/packages/${USER}/pypi -u ${USER} -p ${PASS} --non-interactive --disable-progress-bar --verbose dist/*"
+                }
+            }
+        }
+    }
+}
\ No newline at end of file
diff --git a/environment.yml b/environment.yml
new file mode 100644
index 0000000..9ababcb
--- /dev/null
+++ b/environment.yml
@@ -0,0 +1,9 @@
+name: filterfasta
+channels:
+  - conda-forge
+dependencies:
+  - build=0.7
+  - pytest=7
+  - twine=4
+  - biopython=1.81
+  - python=3.11
diff --git a/pyproject.toml b/pyproject.toml
new file mode 100644
index 0000000..5f8f5e3
--- /dev/null
+++ b/pyproject.toml
@@ -0,0 +1,3 @@
+[build-system]
+build-backend = "setuptools.build_meta"
+requires = ["setuptools", "wheel"]
\ No newline at end of file
diff --git a/setup.cfg b/setup.cfg
new file mode 100644
index 0000000..fac52d5
--- /dev/null
+++ b/setup.cfg
@@ -0,0 +1,10 @@
+[metadata]
+name = filterfasta
+version = 0.0.1
+
+[options]
+packages = filterfasta
+
+[options.entry_points]
+console_scripts =
+    filterfasta = filterfasta.filterfasta:main
\ No newline at end of file
diff --git a/setup.py b/setup.py
new file mode 100644
index 0000000..6068493
--- /dev/null
+++ b/setup.py
@@ -0,0 +1,3 @@
+from setuptools import setup
+
+setup()