began adding PubMLST support
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from Bio import SeqIO
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from automlst.engine.data.mlst import Allele, MLSTProfile
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from automlst.engine.remote.databases.institutpasteur.mlst import InstitutPasteurProfiler
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from automlst.engine.remote.databases.pubmlst.mlst import PubMLSTProfiler
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async def test_profiling_results_in_exact_matches_when_exact():
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dummy_alleles = {
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Allele("adk", "1"),
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Allele("atpG", "1"),
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Allele("frdB", "1"),
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Allele("fucK", "1"),
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Allele("mdh", "1"),
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Allele("pgi", "1"),
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Allele("recA", "5"),
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}
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sequence = str(SeqIO.read("tests/resources/FDAARGOS_1560.fasta", "fasta").seq)
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async with PubMLSTProfiler(database_name="pubmlst_hinfluenzae_seqdef") as dummy_profiler:
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exact_matches = dummy_profiler.fetch_mlst_allele_variants(schema_id=1, sequence_string=sequence)
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async for exact_match in exact_matches:
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assert isinstance(exact_match, Allele)
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dummy_alleles.remove(exact_match)
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assert len(dummy_alleles) == 0
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async def test_profiling_results_in_correct_st():
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dummy_alleles = [
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Allele("adk", "1"),
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Allele("atpG", "1"),
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Allele("frdB", "1"),
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Allele("fucK", "1"),
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Allele("mdh", "1"),
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Allele("pgi", "1"),
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Allele("recA", "5"),
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]
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async with InstitutPasteurProfiler(database_name="pubmlst_hinfluenzae_seqdef") as dummy_profiler:
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mlst_st_data = await dummy_profiler.fetch_mlst_st(1, dummy_alleles)
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assert mlst_st_data is not None
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assert isinstance(mlst_st_data, MLSTProfile)
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assert mlst_st_data.clonal_complex == "ST-3 complex"
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assert mlst_st_data.sequence_type == "3"
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async def test_sequence_profiling_is_correct():
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sequence = str(SeqIO.read("tests/resources/tohama_I_bpertussis.fasta", "fasta").seq)
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async with InstitutPasteurProfiler(database_name="pubmlst_hinfluenzae_seqdef") as dummy_profiler:
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profile = await dummy_profiler.profile_string(1, sequence)
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assert profile is not None
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assert isinstance(profile, MLSTProfile)
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assert profile.clonal_complex == "ST-3 complex"
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assert profile.sequence_type == "3"
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